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          <imsmd:langstring xml:lang="nl">Deze les valt onder de arrangeerbare leerlijn van de Stercollectie voor biologie voor vwo leerjaar 4/5/6. Dit is thema ’Erfelijkheid'. Het onderwerp van deze les is: Herman en Klazien.
Je leert de uitkomst voorspellen van een:
kruising tussen twee individuen met een intermediair fenotype.
kruising waarin multiple allelen een rol spelen.
kruising waarin een letale factor een rol speelt.
een uitspraak doen over:
de kans dat een bepaald individu een bepaald kenmerk heeft aan de hand van stamboomgegevens.
het genotype van bepaalde individuen.
uitleggen wat de begrippen epigenetica, methylering en mitochondriaal DNA inhouden.
de veranderingen in fenotype verklaren met gebruikmaking van de begrippen epigenetica, methylering en mDNA.
een gemotiveerde eigen mening vormen rond een aantal problemen op het gebied van menselijk ingrijpen in de erfelijkheid bij dieren.</imsmd:langstring>
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          <title>Wat ga ik leren?</title>
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                    <imsmd:langstring xml:lang="x-none"/>
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                </imsmd:taxonpath>
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              <imsmd:taxonpath>
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              <imsmd:taxonpath>
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              <imsmd:taxonpath>
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                </imsmd:context>
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                </imsmd:typicalagerange>
                <imsmd:difficulty>
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                    <imsmd:langstring xml:lang="x-none">LOMv1.0</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">medium</imsmd:langstring>
                  </imsmd:value>
                </imsmd:difficulty>
                <imsmd:typicallearningtime>
                  <imsmd:duration>
                    <imsmd:datetime>PT10M</imsmd:datetime>
                  </imsmd:duration>
                </imsmd:typicallearningtime>
              </imsmd:educational>
              <imsmd:rights>
                <imsmd:cost>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">LOMv1.0</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">no</imsmd:langstring>
                  </imsmd:value>
                </imsmd:cost>
                <imsmd:copyrightandotherrestrictions>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/copyrightsandotherrestrictions_nllom_20131202</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">cc-by-sa-40</imsmd:langstring>
                  </imsmd:value>
                </imsmd:copyrightandotherrestrictions>
                <imsmd:description>
                  <imsmd:langstring xml:lang="x-none">http://creativecommons.org/licenses/by-sa/4.0/</imsmd:langstring>
                </imsmd:description>
              </imsmd:rights>
              <imsmd:classification>
                <imsmd:purpose>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/vdex_classification_purpose_czp_20060628.xml</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">discipline</imsmd:langstring>
                  </imsmd:value>
                </imsmd:purpose>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>2b363227-8633-4652-ad57-c61f1efc02c8</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Biologie</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>547e2088-048e-4e4b-9a0c-155a7bfa53f1</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Erfelijke informatie</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>ae9e9b78-e51f-4663-b61a-ab5034ec1709</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Reproductie</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>d220d833-6efe-4b88-86d0-5a556f60b9b4</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Erfelijkheid</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
              </imsmd:classification>
              <imsmd:classification>
                <imsmd:purpose>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/vdex_classification_purpose_czp_20060628.xml</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">educational level</imsmd:langstring>
                  </imsmd:value>
                </imsmd:purpose>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>85d15c83-e2b4-4359-8475-a355591aaa1a</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">VWO 6</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>e2026706-0829-4a4c-b726-9409b6f407e1</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">VWO 4</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>f2513775-3d54-423b-803b-15e06a8c89a8</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">VWO 5</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
              </imsmd:classification>
              <imsmd:classification>
                <imsmd:purpose>
                  <imsmd:source>
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                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">idea</imsmd:langstring>
                  </imsmd:value>
                </imsmd:purpose>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none"/>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>121a0dbc-01d3-4f3a-afe5-b945e162ba97</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Opdracht</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none"/>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>d8738885-30eb-43e5-bc4e-d10c26283d0b</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Zelfstudie</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
              </imsmd:classification>
            </imsmd:lom>
          </metadata>
        </item>
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          <title>Stap 2: Lapjeskatten</title>
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              <imsmd:general>
                <imsmd:title>
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                <imsmd:language>nl</imsmd:language>
              </imsmd:general>
              <imsmd:metametadata>
                <imsmd:metadatascheme>LOMv1.0</imsmd:metadatascheme>
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                  <imsmd:value>
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                </imsmd:learningresourcetype>
                <imsmd:learningresourcetype>
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                  </imsmd:value>
                </imsmd:learningresourcetype>
                <imsmd:intendedenduserrole>
                  <imsmd:source>
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                  </imsmd:source>
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                    <imsmd:langstring xml:lang="x-none">learner</imsmd:langstring>
                  </imsmd:value>
                </imsmd:intendedenduserrole>
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                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">VO</imsmd:langstring>
                  </imsmd:value>
                </imsmd:context>
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                  </imsmd:value>
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                </imsmd:typicallearningtime>
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                  </imsmd:source>
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                    <imsmd:langstring xml:lang="x-none">no</imsmd:langstring>
                  </imsmd:value>
                </imsmd:cost>
                <imsmd:copyrightandotherrestrictions>
                  <imsmd:source>
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                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">cc-by-sa-40</imsmd:langstring>
                  </imsmd:value>
                </imsmd:copyrightandotherrestrictions>
                <imsmd:description>
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                </imsmd:description>
              </imsmd:rights>
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                <imsmd:purpose>
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                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">discipline</imsmd:langstring>
                  </imsmd:value>
                </imsmd:purpose>
                <imsmd:taxonpath>
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                  <imsmd:taxon>
                    <imsmd:id>2b363227-8633-4652-ad57-c61f1efc02c8</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Biologie</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>547e2088-048e-4e4b-9a0c-155a7bfa53f1</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Erfelijke informatie</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>ae9e9b78-e51f-4663-b61a-ab5034ec1709</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Reproductie</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>d220d833-6efe-4b88-86d0-5a556f60b9b4</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Erfelijkheid</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
              </imsmd:classification>
              <imsmd:classification>
                <imsmd:purpose>
                  <imsmd:source>
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                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">educational level</imsmd:langstring>
                  </imsmd:value>
                </imsmd:purpose>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>85d15c83-e2b4-4359-8475-a355591aaa1a</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">VWO 6</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>e2026706-0829-4a4c-b726-9409b6f407e1</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">VWO 4</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">http://purl.edustandaard.nl/begrippenkader</imsmd:langstring>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>f2513775-3d54-423b-803b-15e06a8c89a8</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">VWO 5</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
              </imsmd:classification>
              <imsmd:classification>
                <imsmd:purpose>
                  <imsmd:source>
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                  </imsmd:source>
                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">idea</imsmd:langstring>
                  </imsmd:value>
                </imsmd:purpose>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none"/>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>121a0dbc-01d3-4f3a-afe5-b945e162ba97</imsmd:id>
                    <imsmd:entry>
                      <imsmd:langstring xml:lang="nl">Opdracht</imsmd:langstring>
                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
                <imsmd:taxonpath>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none"/>
                  </imsmd:source>
                  <imsmd:taxon>
                    <imsmd:id>d8738885-30eb-43e5-bc4e-d10c26283d0b</imsmd:id>
                    <imsmd:entry>
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                    </imsmd:entry>
                  </imsmd:taxon>
                </imsmd:taxonpath>
              </imsmd:classification>
            </imsmd:lom>
          </metadata>
        </item>
        <item identifier="Item60bdac0c5f926fcd" identifierref="Resource60bdac0c5f926fcd">
          <title>Stap 3: Muizenissen</title>
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                <imsmd:title>
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                <imsmd:language>nl</imsmd:language>
              </imsmd:general>
              <imsmd:metametadata>
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                  <imsmd:value>
                    <imsmd:langstring xml:lang="x-none">open opdracht</imsmd:langstring>
                  </imsmd:value>
                </imsmd:learningresourcetype>
                <imsmd:intendedenduserrole>
                  <imsmd:source>
                    <imsmd:langstring xml:lang="x-none">LOMv1.0</imsmd:langstring>
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                    <imsmd:langstring xml:lang="x-none">learner</imsmd:langstring>
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                </imsmd:intendedenduserrole>
                <imsmd:context>
                  <imsmd:source>
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                  <imsmd:value>
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                  </imsmd:value>
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                </imsmd:difficulty>
                <imsmd:typicallearningtime>
                  <imsmd:duration>
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                </imsmd:typicallearningtime>
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                    <imsmd:langstring xml:lang="x-none">no</imsmd:langstring>
                  </imsmd:value>
                </imsmd:cost>
                <imsmd:copyrightandotherrestrictions>
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                    <imsmd:langstring xml:lang="x-none">cc-by-sa-40</imsmd:langstring>
                  </imsmd:value>
                </imsmd:copyrightandotherrestrictions>
                <imsmd:description>
                  <imsmd:langstring xml:lang="x-none">http://creativecommons.org/licenses/by-sa/4.0/</imsmd:langstring>
                </imsmd:description>
              </imsmd:rights>
              <imsmd:classification>
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